The IONA TWIN STUDY

| Updated 2 Jul 2020

Objectives • To optimise the technology used in the IONA® test in twin pregnancies. This should also reduce the incidence of test failures related to inability to perform the test due to low fetal fraction. • To explore the performance of the test in different types of twin pregnancies including …
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Fetal Therapy

| Updated 2 Jul 2020


Ultrasound Training

| Updated 2 Jul 2020


Twin Reversed Arterial Perfusion Intervention STudy (TRAPIST)

| Updated 2 Jul 2020

The study main question is whether early intervention (12-14 weeks gestation) improves the survival and the 2-year development of the children compared to late intervention (16-18 weeks gestation) in twin pregnancies complicated by twin reversed arterial perfusion sequence (TRAP). \nTRAP sequence is a complication of a shared circulation in monochorionic …
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Twin pregnancies With complications: Impact on Neurodevelopment Study via Registry Follow up (TWINS-RF)

| Updated 1 Jul 2020

When identical twins share a placenta (monochorionic) they are at increased risk of neurodevelopmental delay (disability), especially when there are problems in the shared blood supply in the placenta (this includes conditions like twin-to-twin transfusion syndrome, twin anaemia polycythaemia sequence and selective fetal growth restriction). The incidence of neurodevelopmental delay …
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Triplet pregnancies

| Updated 1 Jul 2020

Triplets can be non-identical, identical, or mixed chorionicity (e.g. 2 identical and 1 non-identical). They carry higher risks of miscarriage and very early labour than twins, are often smaller than twins, and can also predispose the mother to more risks (pre-eclampsia, bleeding after birth). Identical triplets also carry the risk …
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Monochorionic monoamniotic twins (MCMA)

| Updated 1 Jul 2020

This rare type of identical twins not only share a placenta, but also share the same amniotic sac (pocket of fluid). They carry a higher risk of complications, such as miscarriage, stillbirth, fetal anomalies than identical twins, but also have a risk of cord entanglement. Due to the small numbers …
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Twin anaemia polycythaemia sequence (TAPS)

| Updated 3 Mar 2021

TAPS is an uncommon condition that occurs in identical twins. It results in one twin becoming very anaemic (low blood level), and the other polycythaemic (high blood level). This can occur either on its own, or after laser treatment for TTTS. So far, the best way to treat this condition …
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