MBBS BSc. Hons. PhD FRCP (UK)

Consultant (Interventional) Cardiologist

Honorary Senior Lecturer

Lead for Intervention – Health Education South London

Contact

Secretary: Deborah Squire

Secretary email: Deborah.squire@stgeorges.nhs.uk

Secretary telephone: 020 8725 3576

Secretary fax: 020 8725 3178

Clinical interests

Coronary artery disease / Angioplasty / Invasive physiological assessment of coronary artery disease with Pressure wire, IFR and OCT/IVUS.

Research interests

Endothelial function and endothelial progenitor cells in coronary artery disease.

Local Principal Investigator for complete revascularisation in MI international RCT trial.

Presentations

2010 Endothelial Progenitor Cell biology and Coronary Intervention, Guest Speaker, International Cardiology Symposium, Athens, Greece.

2011 Thymidine phosphorylase determines improvement in endothelial function following cardiac  rehabilitation Astroulakis Z, Chowienczyk P, Mayr M, Shah AM, Hill JM  AHA Scientific Sessions, Orlando, Florida, USA (Nov 2011).

2012 Thymidine phosphorylase plays a critical role in improving endothelial function following acute coronary syndrome  Finalist  BCIS/ ACI Young Investigator Award.

Publications

Outcome of 1,051 Octagenarian Patients with ST-segment Elevation Myocardial Infarction Treated with Primary Percutaneous  Coronary Intervention   J Am Heart Assoc 5(6) Sept 2016.

Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of  endothelial progenitor cells.  Pula G, Mayr U, Evans C, Prokopi M, Xiaoke Y, Astroulakis Z, Qingzhong X, Hill JM, Qingbo X, Mayr M  Circulation Research 2009; 104:32-40.

Endothelial progenitor and stem cells in coronary artery disease (Review). Astroulakis Z, Wojakowski W, Hill JM Leukemia (2012).

Heart Disease in Pregnancy – Oxford Handbook of Cardiology Astroulakis Z, Nelson-Piercy C Oxford University Press (2012).

Chapter 27 Cell Therapy  Interventional Cardiology: Principles and Practice Astroulakis Z, Sirker A, Hill JM  Editors: Di Mario C, Dangas G, Barlis B   Wiley Blackwell 2011.

Does ‘SWITCHing’ from heparin to bivalirudin monotherapy result in a bleeding benefit?Astroulakis Z, Hill JM European Heart Journal 2009; 11:13-18.

The role of vascular progenitor cells in endogenous arterial remodelling in the adult.  Sirker A, Astroulakis Z, Hill JM  Clinical Science 2009; 116:283-299.

Failed endothelialisation of a percutaneous atrial septal defect closure device  Astroulakis Z, El Gamel A, Hill JM Heart 2008; 94:580.

Oxford Handbook of Cardiology Chapter 4 - Coronary Artery Disease   Editors: Ramrakha P and Hill J. ISBN: 0-19-852597-4 Oxford University Press 2006.

Percutaneous intervention to a RCA-SVG complicated by perforation into the right heart Astroulakis Z, Mathur A. Circulation 2006; 114:e549-550.

Local, National and International profile/affiliations

  • Honorary Senior Lecturer – SGUL
  • Lead for Intervention – Health Education South London
  • Lead for Cardiac Simulation Training – Health Education South London