Twin-to-twin transfusion syndrome (TTTS)
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TTTS is a serious condition that can occur in 10-15% of twins sharing one placenta (identical). In severe cases, it can result in death or handicap in 90% of twins if left untreated. Numerous research projects have been carried out to identify the best therapies and techniques to treat this condition, when the treatments should be performed, and the outcomes of the babies after treatment.
At St George’s, we have carried out research projects to find the best treatment for stage 1 (mild) TTTS, identify the outcomes of babies who share both a placenta and an amniotic sac who develop TTTS, and have established a core set of outcomes to be reported in research for babies following TTTS so that we can compare and improve the value of future research.
Evolution of Stage 1 Twin-to-Twin Transfusion Syndrome (TTTS): Systematic Review and Meta-Analysis