Multiple Pregnancy Registry
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This is a UK national initiative endorsed by the Royal College of Obstetricians and Gynaecologists (RCOG), British Maternal Fetal Medicine Society (BMFMS) and the Twin and Multiple Births Association (TAMBA). The aims include: • Systematically tracking complicated multiple pregnancies, triplet and uncomplicated monochorionic twin pregnancies to ascertain pregnancy outcomes and address the gaps in knowledge • Improving patient care in clinical practice • Contributing data to quality benchmarking projects, audits and research studies • Facilitating an easier option to meet near future reporting requirements and performance expectations • Establish a platform to allow long-term follow-up of these infants at a national level. The Registry would allow the possibility of following up a large cohort of twins whose pregnancies were complicated, whether they had treatment or not. These long-term data cannot be determined from short-term clinical trials in selected patients. Some of the neurodevelopmental outcomes cannot be assessed in a robust manner during infancy or early childhood, and most of the studies reporting on the neurodevelopmental outcomes have not followed-up these children beyond the age of two years.
Routinely recorded anonymised data related to mutiple pregnancy will be stored on a secured website database (Registry). The inclusion criteria include complicated multiple pregnancies (twin-to-twin transfusion syndrome, selective fetal growth restriction, twin anaemia polycythaemia sequence, twin reversed arterial perfusion, twin discordant anomaly, single intrauterine demise), triplet pregnancies, and uncomplicated Monochorionic twin pregnancies. The exclusion criteria include uncomplicated dichorionic twin pregnancies
The data will be collected by the local team in each centre contributing to the Registry. The team members performing this task hold a valid good clinical practice (GCP) certificate, to ensure their awareness of clinical governance and the Data Protection Act.