Specialty Registrar in Clinical Pharmacology and Therapeutics and General Internal Medicine

Clinical interests

Dr Threapleton’s clinical interests involve working with patients and healthcare professionals to manage complex long term health conditions and polypharmacy (the use of multiple medicines).  He was instrumental in setting up the new Polypharmacy Service at St George’s.

Academic interests

Dr Threapleton is an honorary clinical lecturer at St George’s, University of London.  His primary research interests are the culture and practice of prescribing and the management of patients with polypharmacy.  He is currently undertaking a PhD to assess how clinical pharmacologists could contribute to the management of this growing phenomenon.

Dr Threapleton was the leader of the Drugs in Healthcare module on the Clinical Pharmacology BSc from 2018 to 2020 and still regularly teaches on the degree.

Professional profile

Dr Threapleton qualified from Newcastle University with a BSc Psychology in 2009 and MBBS Medicine and Surgery in 2013.  He achieved membership to the Royal College of Physicians in 2016.  He is currently undertaking higher specialist training in Clinical Pharmacology and Therapeutics and General Internal Medicine.

Memberships, fellowships and awards

Chair of the Specialty Registrar Sub-Committee of the British Pharmacological Society

Fellow of the British Pharmacological Society

Fellow of the Higher Education Academy

Member of the Royal College of Physicians (London)

Member of the Clinical Committee of the British Pharmacological Society

Member of the Clinical Pharmacology Skills Alliance (CPSA)

Council Member of the European Association for Clinical Pharmacology and Therapeutics

Education Excellence Award, St George’s, University of London, 2020


Click here to view Dr Threapleton’s ResearchGate profile

(in reverse chronological order)

Threapleton CJD, Harris T, Baker EH. Stratifying patients for polypharmacy interventions: The case for a new biomarker? [published online ahead of print, 2021 Oct 1]. Br J Clin Pharmacol. 2021;10.1111/bcp.15083. doi:10.1111/bcp.15083.

Janjua S, Carter D, Threapleton CJ, Prigmore S, Disler RT. Telehealth interventions: remote monitoring and consultations for people with chronic obstructive pulmonary disease (COPD). Cochrane Database Syst Rev. 2021;7(7):CD013196. Published 2021 Jul 20. doi:10.1002/14651858.CD013196.pub2.

Janjua S, Banchoff E, Threapleton CJD, Prigmore S, Fletcher J, Disler RT. Digital interventions for the management of chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2021, Issue 4. Art. No.: CD013246. DOI: 10.1002/14651858.CD013246.pub2.

Janjua S, Mathioudakis AG, Fortescue R, Walker RA, Sharif S, Threapleton CJ, Dias S. Prophylactic antibiotics for adults with chronic obstructive pulmonary disease: a network meta-analysis. Cochrane Database Syst Rev. 2021 Jan 15;1:CD013198.

Threapleton CJD, Kimpton JE, Carey IM, DeWilde S, Cook DG, Harris T, Baker EH. Development of a structured clinical pharmacology review for specialist support for management of complex polypharmacy in primary care. Br J Clin Pharmacol. 2020 Jul;86(7):1326-1335.

Khong TK, Threapleton CJD. Prescribing of anticholinergic medicines to patients initiating dementia medicines. Drug Ther Bull. 2020;58(6):83‐84.

Khong TK, Threapleton CJD. Discharging doctors do not reliably predict risk of medication-related harm. Drug Ther Bull. 2019;57(7):102‐103.

Kimpton JE, Carey IM, Threapleton CJD, et al. Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing. Br J Clin Pharmacol. 2019;85(12):2734‐2746.

Threapleton CJ, Janjua S, Fortescue R, Baker EH. Head-to-head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2019;5(5):CD013024

Walker RW, Churm D, Dewhurst F, Samuel M, Ramsell A, Lawrie C, Hill J, Threapleton CJ, Wood B, Gray WK. Palliative care in people with idiopathic Parkinson’s disease who die in hospital, BMJ Support Palliat Care. 2014 Mar;4(1):64-7.

Robinson LJ, Stevens LH, Threapleton CJ, Vainiute J, McAllister-Williams RH, Gallagher P. Effects of intrinsic and extrinsic motivation on attention and memory. Acta Psychol (Amst). 2012.