ED Clinical Research Unit – Publications

2021 publications (alphabetical)

Cappelletto M, Jarman H (2021) Screening and management of unintentional low-level carbon monoxide exposure in the emergency department. Emergency Nurse. doi: 10.7748/en.2021.e2077

Grassin-Delyle S, Shakur-Still H, Picetti R, Frimley L, Jarman H. et al. Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial. Br J Anaesth. 2021 Jan;126(1):201-209. doi.org/10.1016/j.bja.2020.07.058

Goldsmith L, Anderson K, Clarke G, Crowe C, Jarman H, et al. Psychiatric decision unit as an emerging model in NHS crisis care system: a national survey in England. International Journal of Mental Health Nursing 2021. doi:10.1111/inm.12849

Jarman H, Crouch R, Baxter M, Wang C, Peck G, Sivapathasuntharam D, Jennings C, Cole E. Feasibility and accuracy of ED frailty identification in older trauma patients: a prospective multi-centre study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 2021. doi.org/10.1186/s13049-021-00868-4

Pickard A, Hudson A, Sabri O. The use of ‘viscoelastic tests’ in driving transfusion needs in major trauma patients, Orthopaedics and Trauma 2021. doi.org/10.1016/j.mporth.2021.02.001

2020 publications (alphabetical)

Alghamdi A, Reynard C, Morris N, Moss P, Jarman H, Hardy E, Harris T, Horner D, Parris R, Body R. Diagnostic accuracy of the Troponin-only Manchester Acute Coronary Syndromes (T-MACS) decision aid with a point-of-care cardiac troponin assay. Emerg Med Jour 2020;37(4):223-228 doi.org/10.1136/emermed-2019-208882

Goodacre S, Walters S, Qayyum H, Coffey F, Carlton E, Coats T, Glazebrook W, Unitt L. Diagnostic accurarcy of magnetocardiograph for patients with suspected acute coronary syndrome. Emerg Med Jour 2020 doi.org/10.1136/emermed-2020-210396

Henshall C, Greenfield D, Jarman H, Rostron H, Jones H, Barrett S. A nationwide initiative to increase nursing and midwifery research leadership: overview of year one programme development, implementation and evaluation. J Clin Nurs 2020. doi.org/10.1111/jocn.15558

Hudson A, Gavrilovski M. Adequacy of vascular access in pre-hospital major haemorrhage. London Trauma Conference 2019. Scand J Trauma Resusc Emerg Med 2020, (28)13 doi.org/10.1186/s13049-020-0711-6 [poster]

Jarman H, Crouch R, Baxter M, Cole E, Dillane B, & Wang C. Frailty in major trauma study (FRAIL-T): a study protocol to determine the feasibility of nurse-led frailty assessment in elderly trauma and the impact on outcome in patients with major trauma BMJ Open 2020;10:e038082. doi.org/10.1136/bmjopen-2020-038082

Jones G, Herrera A, Wang C, Moss P, Blazejovaa L. Rapid assessment and discharge, optimizing emergency department bed space allocation: an interrupted time-series analysis. Eur J Emerg Med 2020, 27:64-68 doi:10.1097/MEJ.0000000000000614

Morgan O, Yarham E, Hudson A, Cole E. Do pre-hospital physicians improve mortality in major trauma patients? A systematic review. Trauma. doi.org/10.1177/1460408620953056

Mahmood A, Needham K, Shakur-Still H, Harris T, Jamaluddin S, Davies D, et al. Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a pre-planned substudy in a sample of CRASH-3 trial patients. Emerg Med Jour Published Online First: 01 December 2020 doi.org/10.1136/emermed-2020-210424

Sivayoham N, Blake L et al. Treatment variables associated with outcome in emergency department with suspected sepsis. Annals Intensive Care 2020;10:136  doi.org/10.1186/s13613-020-00747-8

Publications as collaborators

The HALT-IT trial collaborators. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. The Lancet 2020;395(10241):1927-1936 doi.org/10.1016/S0140-6736(20)30848-5 (PDF)

Brenner A, Belli A, Chaudhri R, Coats T et al. Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial. Crit Care 2020;24, 560. doi.org/10.1186/s13054-020-03243-4

2019 publications (alphabetical)

Body R, Twerenbold R, Austin C, Boeddinghaus J, Almashali M, Nestelberger T, Morris N, Badertscher P, McDowell G, Wildi K, Moss P, Jarman H et al. Diagnostic accuracy of a high-sensitivity cardiac troponin assay with a single serum test in the emergency department. Clin Chem 2019; 65(8): 1006-1014 doi.org/10.1373/clinchem.2018.294272

Body R, Almashali M, Morris N, Moss P, Jarman H et al.  Diagnostic accuracy of the T-MACS decision aid with a contemporary point of care troponin assay. Heart 2019; 105(10): 768-774 doi:10.1136/heartjnl-2018-313825

Curry N, Foley C, Wong H, Mora A, Curnow E, Zarankaite A, Hodge R, Hopkins V, Deary A, Ray J, Moss P, Reed M, Kellett S, Davenport R, Stanworth S. The application of a haemorrhage assessment tool in evaluating control of bleeding in a pilot trauma haemorrhage trial. Tranfusion Med 2019, 29(6):454-59. doi: 10.1111/tme.12644

Halter M, Kulnik S, Hilton A, Baron A, Garner S, Jarman H. Lay understanding of head injury and when an ambulance might be needed: a mixed methods study. Emer Med Jour, 2019, 36(10) e11; doi:10.1136/emermed-2019-999abs.24 [poster]

Hudson A, Gavrilovski M. Adequacy of vascular access in pre-hospital major haemorrhage. London Trauma Conference 2019. Scand J Trauma Resusc Emerg Med 2020, (28)13 doi.org/10.1186/s13049-020-0711-6 [poster]

Kulnik ST, Halter M, Jarman H et al. Confidence and willingness among laypersons in the UK to act in a head injury situation: a qualitative focus group study. BMJ Open 2019;9:e033531. doi:10.1136/bmjopen-2019-033531

Leitch P, Hudson A. Incidence of Hyperoxia in HEMS Trauma Patients. London Trauma Conference 2019. Scand J Trauma Resusc Emerg Med 2020, (28)13 doi.org/10.1186/s13049-020-0711-6 [poster]

Morton S, Galea J, Uprichard J, Hudson A. The practicalities and barriers of using TEG6s in code red traumas: an observational study in one London major trauma centre. CJEM 2019. 21(3): 361-364 doi.org/10.1017/cem.2018.426

Saxena, G, Mahdi, A. Rhabdomyolysis as an initial presentation of systemic lupus erythematosus: a case report. Int J Emerg Med 2019, 12(33) doi.org/10.1186/s12245-019-0251-x

Sivayoham N, Blake L, Tharimoopantavida S, Chughtai S, Hussain A, Cecconi M, Rhodes A. The REDS score: a new scoring system to risk-stratify emergency department suspected sepsis: a derivation and validation study. BMJ Open 2019;9:e030922. doi:10.1136/bmjopen-2019-030922

Publications as collaborators

The CRASH-3 Intracranial Bleeding Mechanistic Study Collaborators. Tranexamic acid in traumatic brain injury: an explanatory study nested within the CRASH‑3 trial. Eur J Trauma & Emerg Surg 2020 doi.org/10.1007/s00068-020-01316-1

The CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. Lancet 2019;394:1713-23 doi:10.1016/S0140-6736(19)32233-0

Paediatric Emergency Research in the United Kingdom & Ireland (PERUKI) collaborative. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial. Lancet 2019 doi.org/10.1016/S0140-6736(19)30724-X