• Consultant Interventional Neuroradiologist

    Contact

    Email: jeremy.madigan@stgeorges.nhs.uk

    Secretary: Matisse Mullen

    Secretary email: matisse.mullin@stgeorges.nhs.uk

    Secretary telephone: 020 8725 4481

    Clinical interests

    Dr Madigan is a Consultant Interventional Neuroradiologist (INR) based at the Atkinson Morley Neurosciences Center at St George's Hospital. He specialises in the diagnosis and treatment of neurovascular disorders of the brain and spine. This includes aneurysms, arteriovenous malformations (AVMs), dural arteriovenous fistulae (dAVFs), vasospasm following subarachnoid haemorrhage and acute ischaemic stroke (mechanical thrombectomy).

    He has experience in all aspects of adult diagnostic and interventional neuroradiology, but specific diagnostic interests include neurovascular disease and dementia.

    Professional profile

    Dr Madigan attained a BSc in Chemistry from the University of Otago in New Zealand before training in medicine and qualifying with an MB ChB in 2001. He moved to London in 2003 where he trained in clinical radiology at St George's Hospital, gaining Fellowship of the Royal College of Radiologists in 2007. Between 2008 and 2010 he undertook a fellowship in diagnostic neuroradiology and neurointervention at the National Hospital for Neurology and Neurosurgery, Queen Sqaure. He was appointed as a Consultant Neuroradiologist at St George's Hospital and Honorary Senior Lecturer at St George's Medical School in the Stroke and Dementia Research Centre in May 2010.

    Memberships & Affiliations

    Fellow of the Royal College of Radiologists, London

    British Society of Neuroradiologists

    UK Neurointerventional Group

    European Society of Minimally Invasive Neurological Therapy

    Recent Publications

    Markus HS, Levi C, King A, Madigan J, Norris J; Cervical Artery Dissection in Stroke Study (CADISS) Investigators. Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results. JAMA Neurol. 2019 Jun 1;76(6):657-664. doi: 10.1001/jamaneurol.2019.0072. PubMed PMID: 30801621; PubMed Central PMCID: PMC6563567.

    Markus HS, Levi C, King A, Madigan J, Norris J; Cervical Artery Dissection in Stroke Study (CADISS) Investigators. Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results. JAMA Neurol. 2019 Feb 25. doi: 10.1001/jamaneurol.2019.0072. [Epub ahead of print] PubMed PMID: 30801621.

    Boers AMM, Jansen IGH, Brown S, Lingsma HF, Beenen LFM, Devlin TG, Román LS, Heo JH, Ribó M, Almekhlafi MA, Liebeskind DS, Teitelbaum J, Cuadras P, du Mesnil de Rochemont R, Beaumont M, Brown MM, Yoo AJ, Donnan GA, Mas JL, Oppenheim C, Dowling RJ, Moulin T, Agrinier N, Lopes DK, Aja Rodríguez L, Compagne KCJ, Al-Ajlan FS, Madigan J, Albers GW, Soize S, Blasco J, Davis SM, Nogueira RG, Dávalos A, Menon BK, van der Lugt A, Muir KW, Roos YBWEM, White P, Mitchell PJ, Demchuk AM, van Zwam WH, Jovin TG, van Oostenbrugge RJ, Dippel DWJ, Campbell BCV, Guillemin F, Bracard S, Hill MD, Goyal M, Marquering HA, Majoie CBLM. Mediation of the Relationship Between Endovascular Therapy and Functional Outcome by Follow-up Infarct Volume in Patients With Acute Ischemic Stroke. JAMA Neurol. 2019 Feb 1;76(2):194-202. doi: 10.1001/jamaneurol.2018.3661. PubMed PMID: 30615038.

    Campbell BCV, Majoie CBLM, Albers GW, Menon BK, Yassi N, Sharma G, van Zwam WH, van Oostenbrugge RJ, Demchuk AM, Guillemin F, White P, Dávalos A, van der Lugt A, Butcher KS, Cherifi A, Marquering HA, Cloud G, Macho Fernández JM, Madigan J, Oppenheim C, Donnan GA, Roos YBWEM, Shankar J, Lingsma H, Bonafé A, Raoult H, Hernández-Pérez M, Bharatha A, Jahan R, Jansen O, Richard S, Levy EI, Berkhemer OA, Soudant M, Aja L, Davis SM, Krings T, Tisserand M, San Román L, Tomasello A, Beumer D, Brown S, Liebeskind DS, Bracard S, Muir KW, Dippel DWJ, Goyal M, Saver JL, Jovin TG, Hill MD, Mitchell PJ; HERMES collaborators. Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data. Lancet Neurol. 2019 Jan;18(1):46-55. doi: 10.1016/S1474-4422(18)30314-4. Epub 2018 Nov 6. Erratum in: Lancet Neurol. 2019 Mar;18(3):e2. PubMed PMID: 30413385.

    Boers AMM, Jansen IGH, Beenen LFM, Devlin TG, San Roman L, Heo JH, Ribó M, Brown S, Almekhlafi MA, Liebeskind DS, Teitelbaum J, Lingsma HF, van Zwam WH, Cuadras P, du Mesnil de Rochemont R, Beaumont M, Brown MM, Yoo AJ, van Oostenbrugge RJ, Menon BK, Donnan GA, Mas JL, Roos YBWEM, Oppenheim C, van der Lugt A, Dowling RJ, Hill MD, Davalos A, Moulin T, Agrinier N, Demchuk AM, Lopes DK, Aja Rodríguez L, Dippel DWJ, Campbell BCV, Mitchell PJ, Al-Ajlan FS, Jovin TG, Madigan J, Albers GW, Soize S, Guillemin F, Reddy VK, Bracard S, Blasco J, Muir KW, Nogueira RG, White PM, Goyal M, Davis SM, Marquering HA, Majoie CBLM. Association of follow-up infarct volume with functional outcome in acute ischemic stroke: a pooled analysis of seven randomized trials. J Neurointerv Surg. 2018 Dec;10(12):1137-1142. doi: 10.1136/neurintsurg-2017-013724. Epub 2018 Apr 7. PubMed PMID: 29627794.

    Pauls MM, Moynihan B, Barrick TR, Kruuse C, Madigan JB, Hainsworth AH, Isaacs JD. The effect of phosphodiesterase-5 inhibitors on cerebral blood flow in humans: A systematic review. J Cereb Blood Flow Metab. 2018 Feb;38(2):189-203. doi: 10.1177/0271678X17747177. Epub 2017 Dec 19. PubMed PMID: 29256324; PubMed Central PMCID: PMC5951021.

    Pauls MMH, Clarke N, Trippier S, Betteridge S, Howe FA, Khan U, Kruuse C, Madigan JB, Moynihan B, Pereira AC, Rolfe D, Rostrup E, Haig CE, Barrick TR, Isaacs JD, Hainsworth AH. Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease (PASTIS): study protocol for a randomised controlled trial. Trials. 2017 May 22;18(1):229. doi: 10.1186/s13063-017-1973-9. PubMed PMID: 28532471; PubMed Central PMCID: PMC5440904.

    Larsson SC, King A, Madigan J, Levi C, Norris JW, Markus HS. Prognosis of carotid dissecting aneurysms: Results from CADISS and a systematic review. Neurology. 2017 Feb 14;88(7):646-652. doi: 10.1212/WNL.0000000000003617. PubMed PMID: 28087823

    Muir KW, Ford GA, Messow CM, Ford I, Murray A, Clifton A, Brown MM, Madigan J, Lenthall R, Robertson F, Dixit A, Cloud GC, Wardlaw J, Freeman J, White P; PISTE Investigators.. Endovascular therapy for acute ischaemic stroke: the Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) randomised, controlled trial. J Neural Neurosurg Psychiatry. 2016 Oct 18. pii: jnnp-2016-314117. dos:10.1136/jnnp-2016-314117.

    Madigan JB, Wilcock DM, Hainsworth AH. Vascular Contributions to Cognitive Impairment and Dementia: Topical Review of Animal Models. Stroke. 2016 Jul;47(7):1953-9. doi: 10.1161/STROKEAHA.116.012066.

    Markus, H. S., Hayter, E., Levi, C., Feldman, A., Venables, G., Norris, J., et al. Investigators, C. A. D. I. S. S. T. (2015). Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial. LANCET NEUROLOGY, 14(4), 361-367.

    King, A., Madigan, J., Clifton, A., Norris, J., & Markus, H. S. (2015). Neuro-radiological confirmation of dissection: Lessons learned from a multicenter randomized trial - Cervical Artery Dissection in Stroke Study (CADISS). INTERNATIONAL JOURNAL OF STROKE, 10, 7.

    King, A., Madigan, J., Clifton, A., Norris, J., & Markus, H. S. (2015). Pseudoaneurysms in cervical artery dissection: Results from a multicenter randomized trial - Cervical Artery Dissection in Stroke Study (CADISS). INTERNATIONAL JOURNAL OF STROKE, 10, 83.

    Maratos, E. C., Bridges, L. R., MacKinnon, A. D., Madigan, J. B., Atra, A., & Martin, A. J. (2014). Isolated intracranial Rosai-Dorfman disease in a child, a case report and review of the literature.. Childs Nerv Syst, 30(9), 1595-1600.

    Duxbury, O., Bhogal, P., Cloud, G., & Madigan, J. (2014). Successful treatment of central retinal artery thromboembolism with ocular massage and intravenous acetazolamide.. BMJ Case Rep, 2014.

    McDonald, J. S., Carter, R. E., Layton, K. F., Mocco, J., Madigan, J. B., Tawk, R. G., . . . Kallmes, D. F. (2013). Interobserver variability in retreatment decisions of recurrent and residual aneurysms.. AJNR Am J Neuroradiol, 34(5), 1035-1039.

    Brown, S. C., Brew, S., & Madigan, J. (2011). Investigating suspected subarachnoid haemorrhage in adults.. BMJ, 342, d2644.