Research finds endurance exercise could impact body’s largest artery differently in men and women
Older male athletes could be at higher risk of heart and circulatory diseases than female competitors of a similar age, according to new research presented at the British Cardiovascular Society (BCS) conference in Manchester.
The study, funded by the British Heart Foundation (BHF) and Cardiac Risk in the Young (CRY), showed that older male athletes had a stiffer aorta.
However, experts say the findings should not deter people from exercising, as further research is needed to understand the biological reasons underpinning these differences. They have also urged that regular, moderate intensity exercise is beneficial for heart health.
Researchers from Barts Heart Centre at St Bartholomew’s Hospital, St George’s Hospital and the University College London (UCL) studied over 300 ‘masters’ athletes – those aged over 40 who had taken part in over 10 endurance events and had exercised regularly for at least 10 years.
Half of the athletes were male, whilst the other half were female. The cohort was mainly made up of distance runners but also included cyclists, swimmers and rowers.
Heart MRI scans were used to study the stiffness of the athlete’s aorta – the largest artery in the human body, which carries oxygen-rich blood away from the heart to the rest of the body and the brain.
Researchers from this group had previously developed a method of calculating vascular age, which estimates the age of arteries based on their stiffness. Stiffer arteries are associated with an increased risk of heart and circulatory diseases, such as heart attack and stroke, in non-athletes – but the impact on the cardiovascular health of athletes is not known.
The team discovered that for older male athletes, their aortas were stiffer and, on average, 9.6 years older than their chronological age. However, for female athletes, the vascular age of their aorta was around the same as their chronological age.
They also investigated the vascular age of different sections of the aorta. Researchers found the greatest difference in the descending aorta, which is the section of the aorta that runs through the chest. For male athletes, this was on average 15 years older than their chronological age. But for female athletes, it was, on average, six years younger.
Although the research couldn’t identify why this is the case, it suggests that long-term endurance exercise might impact men differently to women.
Dr Rebecca Hughes, BHF Clinical Research Fellow at UCL and Barts Heart Centre, who led the study said:
“Previous studies into long-term endurance exercise have mainly focused on men, so there is little research available which studies how this impacts female athletes.
“Our research showed that in masters athletes, the aorta is generally stiffer in men and their vascular age is therefore older. But for women, we saw a surprisingly opposite finding, as some areas of their aorta were several years younger than their chronological age.
“In non-athletes, aortic stiffening is associated with heart and circulatory diseases. How this finding applies to potential risk in athletes is not yet fully understood, so more work will be needed to help identify who could be more at risk.”
Professor James Leiper, Associate Medical Director at the British Heart Foundation (BHF), said:
“For athletes who train in endurance exercise, their hearts must work harder to pump blood around the body – and research has shown that in some cases, this can cause changes to the heart.
“This new finding shows the impact this could also have on the main blood vessel in the body and how this differs between men and women. Further research will now be needed to determine the cause of vascular stiffening in male athletes and to assess the impact this might have on other areas of the cardiovascular system before we can make a fully rounded conclusion.
“It is important to note that exercise is proven to reduce the risk of heart and circulatory diseases, helping to control weight and lower both blood pressure and cholesterol. Its benefits far outweigh any potential risks, so the general advice remains to continue moderate intensity exercise regularly.”
To request interviews or for more information please call the BHF press office on 020 7554 0164 or email firstname.lastname@example.org
About the British Heart Foundation
It is only with donations from the public that the BHF can keep its life saving research going. Help us turn science fiction into reality. With donations from the public, the BHF funds ground-breaking research that will get us closer than ever to a world free from the fear of heart and circulatory diseases. A world where broken hearts are mended, where millions more people survive a heart attack, where the number of people dying from or disabled by a stroke is slashed in half. A world where people affected by heart and circulatory diseases get the support they need. And a world of cures and treatments we can’t even imagine today. Find out more at bhf.org.uk